Photo: Piret Ilver / UnsplashIndependent GLP-1 rankings
Rankings and price guides you can check.
FDA-approved GLP-1 medicines, scored in public, with a source and a date on every price.
Top picks
Current top scores
- (01)Weight management
9.0/10
Zepbound
Tirzepatide
Chronic weight management; OSA in adults with obesity.
- (02)Weight management
8.8/10
Wegovy
Semaglutide
Chronic weight management; CV risk reduction per current label.
- (03)Type 2 diabetes
8.4/10
Mounjaro
Tirzepatide
Type 2 diabetes glycemic control in adults.
- (04)Type 2 diabetes
8.2/10
Ozempic
Semaglutide
Type 2 diabetes; CV and kidney risk reduction per label.
From “Best FDA-approved GLP-1 drugs ranked (October 2026)”, updated October 26, 2026. Scores are editorial, not endorsements.
Method
How we rank
A ranking compares public evidence. It is not a suggestion to start a medicine.
- (01)
A public 100-point rubric
Six weighted criteria, from evidence and label fit (25) to UX and support (10). The same weights apply to every ranking.
- (02)
Every price has a source and a date
Manufacturer pages or a captured provider page, with an as-of date on the figure.
- (03)
Payment never moves a score
No affiliate links or ads run today. Illegal and gray-market sellers are not in the rankings.
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Scorecards and head-to-heads for FDA-approved GLP-1 options.
Browse rankings →Telehealth

Providers ranked by total monthly cost, and who we rejected.
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List price, self-pay and insured copay, kept apart.
Read the guide →Guides

Pricing and buying guides, including how to fill a prescription safely.
All guides →Our standards
Why trust the numbers
FDA-approved first
Brand medicines and licensed pharmacy paths. Compounded products are explained, not shopped.
No personal dosing
Start, stop, and switch decisions stay with a clinician who knows your history.